Professor Michael Francis O'Rourke was a distinguished cardiologist whose pioneering career spanned more than six decades at the forefront of cardiovascular medicine in Australia. He earned his medical degree (MBBS) from the University of Sydney in 1960 and subsequently completed his Doctor of Medicine (MD) under Professor Michael Taylor at the same institution. Beginning his professional journey as a Resident and Registrar in Anaesthesia at St. Vincent's Hospital Sydney, he transitioned to cardiology where he established and directed the Coronary Care Unit from 1971, creating a model that would be replicated across Australia. Professor O'Rourke maintained a lifelong academic affiliation with the University of New South Wales, eventually being awarded a Personal Chair in Medicine and the status of Emeritus Professor upon his retirement. His foundational work in cardiac care and hemodynamics established him as one of Australia's most influential medical researchers.
Professor O'Rourke pioneered the integration of pulse wave analysis with conventional blood pressure measurement, developing the SphygmoCor system through his company AtCor Medical which he founded in 1994. This groundbreaking technology for noninvasive measurement of arterial stiffness and central aortic pressure became the global industry standard for decades, revolutionizing cardiovascular assessment worldwide. His research extended to pivotal multicenter trials of recombinant tissue plasminogen activator (rtPA) as a clot-buster therapy for heart attacks, significantly advancing acute coronary care protocols internationally. Additionally, his early work on aortic counterpulsation for cardiogenic shock following myocardial infarction established critical treatment approaches that saved countless lives and shaped modern cardiac intensive care practices across multiple continents.
Beyond his technical innovations, Professor O'Rourke championed the deployment of external cardioverter defibrillators in public spaces, successfully lobbying for their adoption on airlines beginning with Qantas, thereby establishing life-saving protocols that have been implemented globally. His leadership in community defibrillation programs and pre-hospital coronary care transformed emergency cardiac response systems across numerous countries, saving countless lives through early intervention. As a dedicated educator and mentor, he trained generations of medical professionals and paramedic staff, earning formal recognition for his service to medicine. Professor O'Rourke's visionary work continues to influence cardiovascular medicine through the widespread adoption of his methodologies and the ongoing research of his many academic descendants worldwide.