Dr. Jie Wang is a distinguished Principal Investigator at the Songjiang Institute, Shanghai Jiao Tong University School of Medicine, where he leads pioneering research at the intersection of neuroscience and advanced imaging technologies. He holds a joint PhD from Yale University in Biomedical Engineering and Lanzhou University in Chemistry, reflecting his unique interdisciplinary background that bridges engineering and medical sciences. Prior to his current position beginning in 2024, Dr. Wang served as a Professor at the Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences from 2017 to 2024, building on his earlier roles as Associate Professor and Assistant Researcher at the Institute of Physics and Mathematics, Chinese Academy of Sciences. His international research experience includes a postdoctoral fellowship at Yale University, establishing him as a globally recognized expert in brain imaging and neural circuit analysis.
Dr. Wang's research program has revolutionized the integration of magnetic resonance imaging (MRI) with cutting-edge neuroscience techniques including optogenetics, pharmacogenetics, fiber-optic calcium recording, and electrophysiology to investigate the neural mechanisms underlying anesthesia and sleep disorders. His groundbreaking work on genetically encoded MRI technology, developed through innovative viral tracing methods, enables unprecedented whole-brain detection of specific cell types in vivo, representing a major methodological advancement in neuroscience research. By systematically analyzing human brain MRI data with comparative analysis before and after treatment, his team has identified distinctive brain imaging features and potential intervention target regions for insomnia and psychiatric disorders, laying the foundation for novel clinical applications. This translational approach has positioned his research at the forefront of bridging basic neuroscience discoveries with practical clinical solutions for neurological conditions.
As a leader in translational neuroscience, Dr. Wang has established a collaborative research environment that bridges engineering, neuroscience, and clinical medicine, fostering interdisciplinary partnerships across multiple institutions. His laboratory continues to advance non-pharmacological therapies for insomnia disorders while refining the precision of brain imaging techniques for improved diagnostic capabilities. Dr. Wang's work on systematically integrating multiple advanced neuroscience technologies has influenced research methodologies across the field, setting new standards for investigating complex brain disorders. Looking ahead, his research program aims to transform the understanding and treatment of anesthesia mechanisms and sleep disorders through continued innovation in neuroimaging technologies, with the ultimate goal of developing more effective, personalized interventions for patients suffering from neurological conditions.