Professor Jaime Bosch was a world-renowned clinician-scientist whose distinguished career shaped the field of hepatology for over five decades. Born in Girona, Catalonia on August 10, 1947, he graduated top of his class from the University of Barcelona Medical School in 1970 and obtained his PhD in 1973. After completing his clinical training at the Hospital Clínic of the University of Barcelona, he joined its Liver Unit in 1979, establishing one of the world's foremost centers for hepatology research. Between 1980 and 1982, he trained under Professor Roberto Groszmann at Yale University, forging a lifelong scientific partnership that would significantly advance the field of portal hypertension. Since 2015, he served as Guest Professor of Hepatology at the University Hospital Bern, where he played an instrumental role in supporting the liver clinic and mentoring the next generation of hepatologists.
Professor Bosch developed one of the world's most influential research laboratories on portal hypertension, integrating advances in vascular biology to transform the understanding and management of liver complications. His pioneering work significantly advanced the clinical management of variceal bleeding, established non-invasive techniques for measuring portal pressure, and demonstrated the therapeutic potential of statins in liver disease. As a prolific academic, he authored more than 400 peer-reviewed articles and led numerous randomized clinical trials that directly improved care for thousands of patients worldwide. His early focus on hepatorenal syndrome laid the foundation for his career-long dedication to improving the understanding and treatment of portal hypertension and related liver conditions. Through his international collaborations with leading liver units including Yale, Faulkner Hospital, and the Royal Free Hospital in London, his research methodologies became global standards in hepatology practice.
A dedicated member of EASL, Professor Bosch served on the Scientific Committee from 1980 to 1983 and contributed to the Journal of Hepatology as Associate Editor from 2004, shaping the field through editorial leadership. Mentoring a generation of hepatologists worldwide, he established scientific partnerships that continue to drive innovation in liver disease research and treatment protocols. In recognition of his outstanding career and ongoing contributions to the field, he was awarded the prestigious EASL Recognition Award in 2006, cementing his legacy as a transformative figure in hepatology. His lifelong scientific partnership with Professor Roberto Groszmann exemplified his collaborative approach to advancing medical knowledge through international scientific cooperation. Though he passed away on July 15, 2025, Professor Bosch's pioneering research continues to influence clinical practice and inspire hepatologists around the globe, ensuring his enduring impact on liver disease management for generations to come.