Dr. Howard Weiner is a distinguished neurologist and internationally recognized leader in multiple sclerosis research with over five decades of contributions to neurological medicine. He currently serves as the Robert L. Kroc Professor of Neurology at Harvard Medical School and Co-Director of the Ann Romney Center for Neurological Diseases at Brigham and Women's Hospital. Dr. Weiner received his medical degree from the University of Colorado School of Medicine in 1969 and completed his neurology training through the Harvard Longwood Neurological Training Program. His distinguished career has been marked by visionary leadership in establishing major research centers and developing innovative approaches to understanding neurological disorders.
Dr. Weiner has pioneered transformative research in multiple sclerosis and autoimmune neurological conditions for more than twenty five years, fundamentally reshaping therapeutic approaches to these complex diseases. His groundbreaking work on immune tolerance mechanisms led to the founding of Autoimmune, Inc. in 1994, a biotechnology company that developed novel applications of oral tolerance for treating multiple sclerosis, rheumatoid arthritis, and type 1 diabetes. His current research focuses on nasal tolerance therapies using anti-CD3 monoclonal antibody for conditions including multiple sclerosis, Alzheimer's disease, and ALS, with clinical trials demonstrating significant therapeutic potential. These translational research efforts have bridged the gap between fundamental immunology and clinical neurology, creating new treatment paradigms that have influenced medical practice worldwide.
As founder and director of the Partners Multiple Sclerosis Center at Brigham and Women's and Massachusetts General Hospitals, Dr. Weiner has cultivated one of the world's preeminent research and clinical programs for multiple sclerosis treatment and investigation. He co-established the Center for Neurologic Diseases at Brigham and Women's Hospital in 1985, which now encompasses more than 300 scientists and research personnel working across multiple neurological disorders including Alzheimer's, Parkinson's, and ALS. Dr. Weiner's scholarly contributions extend to his influential medical text 'Neurology for the House Officer,' now in its seventh edition, which has trained generations of neurologists. Currently, he continues to drive innovation in neurological disease research through his leadership of the Ann Romney Center and his scientific advisory roles with biotechnology companies developing novel neurological therapeutics.
