Dr. Christos Mantzoros is a distinguished medical researcher and clinician widely recognized as a global authority in endocrinology and metabolism. He currently serves as Professor of Medicine at Harvard Medical School and Adjunct Professor of Medicine at Boston University School of Medicine. Dr. Mantzoros holds leadership positions as Chief of Endocrinology, Diabetes and Metabolism at the Boston VA Healthcare System and Director of Human Nutrition at Beth Israel Deaconess Medical Center. With extensive clinical expertise, he is board certified in Internal Medicine, Endocrinology, Diabetes and Metabolism, as well as Clinical Nutrition, establishing him as a comprehensive specialist in metabolic disorders.
Dr. Mantzoros has pioneered groundbreaking research in obesity, energy homeostasis, and metabolic disorders, with his seminal 1999 review on leptin in Annals of Internal Medicine becoming a cornerstone reference in the field. His laboratory has conducted over 135 clinical trials and published more than 1,000 peer-reviewed articles that have received over 170,000 citations, demonstrating exceptional impact on metabolic science. His work has resulted in multiple patents for diagnostic and therapeutic applications, directly contributed to pharmaceutical development for metabolic disorders, and catalyzed the creation of biotechnology companies including Intekrin, Inc. His research program integrates genomics, animal physiology, molecular biology, and human clinical studies to elucidate novel molecular pathways in energy balance, with significant implications for treating obesity, diabetes, and related malignancies.
Beyond his research achievements, Dr. Mantzoros has mentored over 200 trainees throughout his career, building a vast network of scientists who continue to advance metabolic research worldwide. He serves as editor-in-chief of Metabolism: Clinical and Experimental journal, shaping scholarly discourse in the field, and has established innovative clinical training programs that bridge nutrition science with medical practice. His current research focuses on utilizing physiological, pharmacological, and dietary interventions along with neurocognitive and neuroimaging tools to investigate brain-peripheral organ interactions in energy regulation. Dr. Mantzoros heads Mantzoros Consulting, LLC, providing expertise to pharmaceutical companies, and continues to translate scientific discoveries into tangible clinical benefits for patients with metabolic disorders.
