Professor Bruno Dubois represents a leading authority in neurological research with an illustrious career centered at Paris's prestigious Hôpital de la Pitié-Salpêtrière. He currently serves as Professor of Neurology at the Neurological Institute of the Salpétrière University Hospital affiliated with Sorbonne University and directs both the Behavioural Neurology Department and the Dementia Research Center. As Director of the Research Unit Inserm U-610 at the Institut du Cerveau et de la Moelle Epinière (ICM), he oversees critical neuroscience initiatives that have shaped contemporary understanding of neurodegenerative disorders. His academic journey has established him as one of Europe's foremost experts in Alzheimer's disease and related cognitive impairments.
Professor Dubois has produced groundbreaking research on anatomical and biochemical studies of central cholinergic systems in both rodents and humans, significantly advancing our knowledge of neurodegenerative mechanisms. His work in cognitive neuropharmacology and neuropsychology of dementia patients, particularly regarding memory and executive functions, has provided essential insights for clinical practice and research methodologies. He orchestrated the influential Expert Consensus on new diagnostic criteria for Alzheimer's disease and led the Task Force developing criteria for Parkinson's disease dementia, fundamentally transforming how these conditions are identified worldwide. His direction of the INSIGHT-preAD study revealed important mechanisms of intellectual compensation in Alzheimer's patients, opening innovative pathways for early intervention strategies and therapeutic approaches.
Beyond his research contributions, Professor Dubois serves as a vital connector within the international neuroscience community as a member of the European Alzheimer Disease Consortium and through numerous collaborative research programs. His recent publication 'Alzheimer, la vérité sur la maladie du siècle' challenges prevailing misconceptions about Alzheimer's being merely 'senile dementia' and advocates for deeper scientific and societal understanding of this complex condition. With demographic projections indicating rising Alzheimer's cases across Europe, his work continues to guide clinical protocols, research priorities, and public health policies for addressing this growing challenge. Professor Dubois remains at the vanguard of developing innovative diagnostic approaches and therapeutic strategies that promise to transform how society confronts neurodegenerative diseases in the coming decades.
