Dr. Augustus John Rush is an internationally renowned psychiatrist whose career has spanned over five decades of groundbreaking clinical research and academic leadership. Currently serving as Professor Emeritus at Duke-NUS Medical School, National University of Singapore, he also maintains his position as Adjunct Professor of Psychiatry and Behavioral Sciences at Duke University School of Medicine. Dr. Rush received his bachelor's degree in biochemistry from Princeton University in 1964 and his medical degree from Columbia University College of Physicians & Surgeons in 1968, followed by psychiatric residency at the Hospital of the University of Pennsylvania where he co-established the Depression Clinic with Dr. Manoochehr Khatami. His distinguished career includes significant leadership roles such as Vice Dean for Clinical Sciences at Duke-NUS beginning in 2008 and previous positions at the University of Texas Southwestern Medical Center where he served as Professor and Vice Chair in the Department of Clinical Sciences.
Dr. Rush's pioneering research has fundamentally transformed the understanding and treatment of mood disorders, particularly depressive and bipolar conditions, with over 800 scientific publications that have garnered more than 187,000 citations according to Google Scholar. He played a crucial role in the development and testing of cognitive therapy for bipolar disorder and adolescent depression, significantly expanding the therapeutic landscape for these challenging conditions through collaboration with his mentor Aaron T. Beck. His work on measurement-based care and clinical practice guidelines has established new standards for depression treatment worldwide, improving patient outcomes through systematic, evidence-based approaches that integrate innovative assessment tools with tailored interventions. Dr. Rush's research has been particularly influential in recognizing and managing difficult-to-treat depressions, leading to more personalized and effective treatment strategies that have been adopted across clinical settings internationally.
Beyond his direct research contributions, Dr. Rush has profoundly shaped the field through his editorial leadership as former Associate Editor of both the American Journal of Psychiatry and Biological Psychiatry, influencing the direction of psychiatric research dissemination. His recognition as one of the World's Most Influential Scientific Minds by Thomson Reuters in 2014 underscores the global impact of his work, which has been honored with Lifetime Research Awards from the American Psychiatric Association, the American College of Psychiatrists, and multiple other professional organizations. Currently serving as CEO of Curbstone Consultant LLC, Dr. Rush continues to provide research and organizational consultation to commercial, governmental, academic, and non-profit organizations while mentoring the next generation of psychiatric researchers. His ongoing work focuses on developing innovative treatments for mood disorders through medications, brain stimulation techniques, psychotherapeutic approaches, and disease management protocols, ensuring his legacy of translational research excellence continues to advance psychiatric care worldwide.